Yellow Fever Vaccine in Singapore
Same Day Appointment Available
MOH-Designated Yellow Fever Vaccination Centre
$272 per dose – includes your International Certificate of Vaccination
- Certificate issued on the spot, no separate visit needed
- Gentle injection technique — patients consistently tell us it barely registers
- Convenient, easy to fit around a pre-travel errand run
Prologue Clinic is a Ministry of Health (MOH)-designated Yellow Fever Vaccination Centre. If you’re travelling to or transiting through a country with risk of yellow fever transmission, we can vaccinate you and issue your International Certificate of Vaccination on the same visit.
What Is the Yellow Fever Vaccine and Do I Need It?
The yellow fever vaccine is a single-dose live attenuated vaccination that protects against yellow fever, a mosquito-borne viral disease found in tropical parts of Africa and Central and South America.
You need it if you’re travelling to a country where yellow fever is present, or if that country requires proof of vaccination for entry. You also need it to re-enter Singapore: ICA requires all travellers –including Singapore citizens and residents– who have been in a country with risk of yellow fever transmission within the past six days to show a valid vaccination certificate on arrival.
Which Countries Require Yellow Fever Vaccination?
Yellow fever risk countries are concentrated in tropical areas in Africa, Central and South America. Requirements vary by country and can change – our doctors can confirm what’s required for your specific itinerary during your consultation.
Do I Need the Yellow Fever Vaccine If I'm Only Transiting, Not Visiting?
Yellow fever risk countries are concentrated in tropical areas in Africa, Central and South America. Requirements vary by country and can change – our doctors can confirm what’s required for your specific itinerary during your consultation.
How Long Does the Yellow Fever Vaccine Last?
The yellow fever vaccine lasts for life; a single dose provides lifelong immunity. However, a booster dose may be required for certain individuals, such as those travelling to higher risk countries.
When Should I Get Vaccinated for Yellow Fever Before Travelling?
At least 10 days before you depart. Your International Certificate of Vaccination only becomes legally valid 10 days after your jab, not the day you receive it.
If you arrive in Singapore or at your destination country before your certificate is valid, you may face quarantine or be denied entry. Book your appointment well ahead of your trip to avoid this.
Are There Side Effects of Yellow Fever Vaccine?
The yellow fever vaccine is generally well tolerated. Most people experience only mild reactions, and serious reactions are rare.
Common side effects
- Headache
- Muscle aches
- Low-grade fever
- Soreness at the injection site
Who should not get vaccinated (or needs a medical assessment first)
- Infants under 9 months
- Anyone with a severe allergy to eggs, gelatin, or a previous dose of the vaccine
- Individuals who are weakened immune system (e.g. cancer, HIV, immunosuppressive medications)
- Individuals with thymus disorder or removal, or open heart surgery
- Pregnant or breastfeeding women
If you’re unsure whether you’re eligible, speak with our doctor before booking.
Getting Your International Certificate of Vaccination at Prologue Clinic
As an MOH-designated Yellow Fever Vaccination Centre, Prologue Clinic administers the vaccine and issues your official International Certificate of Vaccination on the same visit. There is no separate appointment or waiting period to get your paperwork.
Why Choose Prologue Clinic for Your Yellow Fever Vaccination
Same-day appointments
No long lead times when your trip is coming up fast.
Certificate issued on the spot
Walk out with your International Certificate of Vaccination in hand, ready for immigration.
A gentle hand with the needle
Our doctors are known for a light, careful injection technique, so the jab itself is over quickly and comfortably.
Cost and Booking
The yellow fever vaccine at Prologue Clinic costs $272, inclusive of your consultation and International Certificate of Vaccination. Book your appointment at least 10 days before you travel to make sure your certificate is valid in time.
Travelling somewhere that also recommends a flu vaccine? Ask about getting both done in the same visit.
Complete Your Trip Prep: Prologue Travel Pouch
Already here for your vaccine? Take the guesswork out of packing for common travel illnesses with the Prologue Travel Pouch – a doctor-curated kit of essential medication for the issues that most often derail a trip: fever, food poisoning, and the common flu.
Adult Travel Pouch – $56
Paediatric Travel Pouch – $60
Buy Prologue’s Travel Pouch online, or ask our team about it on the day.
Ready for Your Trip?
If yellow fever vaccination is required for your destination or transit, don’t leave it until the last minute. Remember that your International Certificate of Vaccination only becomes valid 10 days after vaccination, so booking early can help you avoid unnecessary travel disruptions.
Frequently Asked Questions
What happens if I travel without getting vaccinated?
If you travel to or transit through an at-risk country without vaccination, you may be denied entry at your destination, and you’ll face quarantine of up to 6 days on arrival back in Singapore under the Infectious Disease Act. Yellow fever itself can also range from mild illness to severe, life-threatening disease — vaccination remains the only real prevention.
Is the yellow fever vaccine mandatory to enter Singapore?
It’s mandatory only if you’ve travelled to or transited through a country with risk of yellow fever transmission in the 6 days before arriving in Singapore. If that applies to you, ICA requires a valid International Certificate of Vaccination on arrival.
How long before travel do I need to get vaccinated?
At least 10 days before you travel – that’s when your certificate becomes legally valid.
Does the certificate expire?
No. Since WHO’s 2016 ruling, protection and certification are valid for life.
What happens if I arrive without a valid certificate?
If you’ve travelled from an at-risk country in the past 6 days without one, you may be quarantined for up to 6 days under the Infectious Disease Act.
Can babies get the yellow fever vaccine?
Very young infants are generally not eligible. Speak to our doctor to confirm eligibility for your child’s specific age and health status.
How much does it cost?
$272 at Prologue Clinic, including your International Certificate of Vaccination.
Do I need a booster if I was vaccinated years ago?
Not for most travellers – a single dose lasts a lifetime. Boosters are only occasionally advised for specific outbreak-related travel; check with our doctor if this applies to you.
Is Prologue Clinic an MOH-designated yellow fever vaccination centre?
Yes, we’re licensed by the Ministry of Health to administer the vaccine and issue the official International Certificate of Vaccination.